Toll-like receptor 4 (TLR4) expression is correlated with T2* iron deposition in response to doxorubicin treatment: cardiotoxicity risk assessment

Although doxorubicin (Dox) is an effective antitumor antibiotic in the anthracycline class, it often induces the undesirable side effect of cardiomyopathy leading to congestive heart failure, which limits its clinical use. The primary goal of this study is to evaluate a reliable translational method...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Trofenciuc, Nelu-Mihai, Bordejevic, Aurora Diana, Tomescu, Mirela Cleopatra, Petrescu, Lucian, Crisan, Simina, Geavlete, Oliviana, Mischie, Alexandru, Onel, Alexandru Fica Mircea, Sasu, Alciona, Pop-Moldovan, Adina Ligia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7552385/
https://ncbi.nlm.nih.gov/pubmed/33046755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73946-9
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