Toll-like receptor 4 (TLR4) expression is correlated with T2* iron deposition in response to doxorubicin treatment: cardiotoxicity risk assessment

Although doxorubicin (Dox) is an effective antitumor antibiotic in the anthracycline class, it often induces the undesirable side effect of cardiomyopathy leading to congestive heart failure, which limits its clinical use. The primary goal of this study is to evaluate a reliable translational method...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Trofenciuc, Nelu-Mihai, Bordejevic, Aurora Diana, Tomescu, Mirela Cleopatra, Petrescu, Lucian, Crisan, Simina, Geavlete, Oliviana, Mischie, Alexandru, Onel, Alexandru Fica Mircea, Sasu, Alciona, Pop-Moldovan, Adina Ligia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7552385/
https://ncbi.nlm.nih.gov/pubmed/33046755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73946-9
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