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Interplay of Enzyme Therapy and Dietary Management of Murine Homocystinuria

Albeit effective, methionine/protein restriction in the management of classical homocystinuria (HCU) is suboptimal and hard to follow. To address unmet need, we developed an enzyme therapy (OT-58), which effectively corrected disease symptoms in various mouse models of HCU in the absence of methioni...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nutrients
Hauptverfasser: Park, Insun, Bublil, Erez M., Glavin, Frank, Majtan, Tomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7551847/
https://ncbi.nlm.nih.gov/pubmed/32971905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu12092895
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