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Interplay of Enzyme Therapy and Dietary Management of Murine Homocystinuria

Albeit effective, methionine/protein restriction in the management of classical homocystinuria (HCU) is suboptimal and hard to follow. To address unmet need, we developed an enzyme therapy (OT-58), which effectively corrected disease symptoms in various mouse models of HCU in the absence of methioni...

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Detalhes bibliográficos
Publicado no:Nutrients
Main Authors: Park, Insun, Bublil, Erez M., Glavin, Frank, Majtan, Tomas
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7551847/
https://ncbi.nlm.nih.gov/pubmed/32971905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu12092895
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