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Role of the Helix-8 and C-Terminal Tail in Regulating Proteinase Activated Receptor 2 Signaling

[Image: see text] The C-terminal tail of G-protein-coupled receptors (GPCR) contain important regulatory sites that enable interaction with intracellular signaling effectors. Here we examine the relative contribution of the C-tail serine/threonine phosphorylation sites (Ser(383–385), Ser(387)–Thr(39...

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Detalhes bibliográficos
Publicado no:ACS Pharmacol Transl Sci
Main Authors: Thibeault, Pierre E., Ramachandran, Rithwik
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7551709/
https://ncbi.nlm.nih.gov/pubmed/33073187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00039
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