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Production of Highly Active Recombinant Dermonecrotic Toxin of Bordetella Pertussis

Pathogenic Bordetella bacteria release a neurotropic dermonecrotic toxin (DNT) that is endocytosed into animal cells and permanently activates the Rho family GTPases by polyamination or deamidation of the glutamine residues in their switch II regions (e.g., Gln63 of RhoA). DNT was found to enable hi...

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Bibliografiske detaljer
Udgivet i:Toxins (Basel)
Main Authors: Stanek, Ondrej, Linhartova, Irena, Holubova, Jana, Bumba, Ladislav, Gardian, Zdenko, Malandra, Anna, Bockova, Barbora, Teruya, Shihono, Horiguchi, Yasuhiko, Osicka, Radim, Sebo, Peter
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7551409/
https://ncbi.nlm.nih.gov/pubmed/32942577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12090596
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