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Production of Highly Active Recombinant Dermonecrotic Toxin of Bordetella Pertussis

Pathogenic Bordetella bacteria release a neurotropic dermonecrotic toxin (DNT) that is endocytosed into animal cells and permanently activates the Rho family GTPases by polyamination or deamidation of the glutamine residues in their switch II regions (e.g., Gln63 of RhoA). DNT was found to enable hi...

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Detalles Bibliográficos
Publicado en:Toxins (Basel)
Main Authors: Stanek, Ondrej, Linhartova, Irena, Holubova, Jana, Bumba, Ladislav, Gardian, Zdenko, Malandra, Anna, Bockova, Barbora, Teruya, Shihono, Horiguchi, Yasuhiko, Osicka, Radim, Sebo, Peter
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7551409/
https://ncbi.nlm.nih.gov/pubmed/32942577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12090596
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