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Two Toxic Lipid Aldehydes, 4-hydroxy-2-hexenal (4-HHE) and 4-hydroxy-2-nonenal (4-HNE), Accumulate in Patients with Chronic Kidney Disease

Lipid aldehydes originating from the peroxidation of n-3 and n-6 polyunsaturated fatty acids are increased in hemodialysis (HD) patients, a process already known to promote oxidative stress. However, data are lacking for patients with chronic kidney disease (CKD) before the initiation of HD. We pros...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Soulage, Christophe O., Pelletier, Caroline C., Florens, Nans, Lemoine, Sandrine, Dubourg, Laurence, Juillard, Laurent, Guebre-Egziabher, Fitsum
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7551374/
https://ncbi.nlm.nih.gov/pubmed/32899405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12090567
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