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Merkel Cell Polyomavirus Large T Antigen Unique Domain Regulates Its Own Protein Stability and Cell Growth

Merkel cell polyomavirus (MCV) is the only known human oncogenic virus in the polyomaviridae family and the etiological agent of most Merkel cell carcinomas (MCC). MCC is an aggressive and highly metastatic skin cancer with a propensity for recurrence and poor prognosis. Large tumor antigen (LT), is...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Nwogu, Nnenna, Ortiz, Luz E., Kwun, Hyun Jin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7551350/
https://ncbi.nlm.nih.gov/pubmed/32962090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12091043
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