Pyruvate Kinase M2 Promotes Prostate Cancer Metastasis Through Regulating ERK1/2-COX-2 Signaling

Pyruvate kinase M2 (PKM2) is a key enzyme of glycolysis, which is highly expressed in many tumor cells, and has emerged as an important player in tumor progression and metastasis. However, the functional roles of PKM2 in tumor metastasis remain elusive. Here we showed that PKM2 promoted prostate can...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Oncol
Prif Awduron: Guo, Wenjing, Zhang, Zhishuai, Li, Guihuan, Lai, Xiaoju, Gu, Ruonan, Xu, Wanfu, Chen, Hua, Xing, Zhe, Chen, Liping, Qian, Jiabi, Xu, Shiyuan, Zeng, Fangyin, Deng, Fan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Oncology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550821/
https://ncbi.nlm.nih.gov/pubmed/33117682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.544288
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