Pyruvate Kinase M2 Promotes Prostate Cancer Metastasis Through Regulating ERK1/2-COX-2 Signaling

Pyruvate kinase M2 (PKM2) is a key enzyme of glycolysis, which is highly expressed in many tumor cells, and has emerged as an important player in tumor progression and metastasis. However, the functional roles of PKM2 in tumor metastasis remain elusive. Here we showed that PKM2 promoted prostate can...

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Foilsithe in:Front Oncol
Main Authors: Guo, Wenjing, Zhang, Zhishuai, Li, Guihuan, Lai, Xiaoju, Gu, Ruonan, Xu, Wanfu, Chen, Hua, Xing, Zhe, Chen, Liping, Qian, Jiabi, Xu, Shiyuan, Zeng, Fangyin, Deng, Fan
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2020
Ábhair:
Oncology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550821/
https://ncbi.nlm.nih.gov/pubmed/33117682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.544288
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