Pyruvate Kinase M2 Promotes Prostate Cancer Metastasis Through Regulating ERK1/2-COX-2 Signaling

Pyruvate kinase M2 (PKM2) is a key enzyme of glycolysis, which is highly expressed in many tumor cells, and has emerged as an important player in tumor progression and metastasis. However, the functional roles of PKM2 in tumor metastasis remain elusive. Here we showed that PKM2 promoted prostate can...

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
Wydane w:Front Oncol
Główni autorzy: Guo, Wenjing, Zhang, Zhishuai, Li, Guihuan, Lai, Xiaoju, Gu, Ruonan, Xu, Wanfu, Chen, Hua, Xing, Zhe, Chen, Liping, Qian, Jiabi, Xu, Shiyuan, Zeng, Fangyin, Deng, Fan
Format: Artigo
Język:Inglês
Wydane: Frontiers Media S.A. 2020
Hasła przedmiotowe:
Oncology
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550821/
https://ncbi.nlm.nih.gov/pubmed/33117682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.544288
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