Cholinergic Dysfunction Involvement in Chronic Cerebral Hypoperfusion-Induced Impairment of Medial Septum–dCA1 Neurocircuit in Rats

Chronic cerebral hypoperfusion (CCH) is considered a preclinical condition of mild cognitive impairment and thought to precede dementia. However, as the principal cholinergic source of hippocampus, whether the septo-hippocampal neurocircuit was impaired after CCH is still unknown. In this study, we...

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Pubblicato in:Front Cell Neurosci
Autori principali: Xu, Yi, Zhang, Shuai, Sun, Qiang, Wang, Xu-Qiao, Chai, Ya-Ni, Mishra, Chandan, Chandra, Shah Ram, Ai, Jing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Cellular Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550820/
https://ncbi.nlm.nih.gov/pubmed/33132852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.586591
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