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Transgenic Chlamydomonas Expressing Human Transient Receptor Potential Ankyrin 1 (TRPA1) Channels to Assess the Effect of Agonists and Antagonists

Transient receptor potential ankyrin 1 (TRPA1) channel is an ion channel whose gating is controlled by agonists, such as allyl isothiocyanate (AITC), and temperature. Since TRPA1 is associated with various disease symptoms and chemotherapeutic side effects, it is a frequent target of drug developmen...

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Veröffentlicht in:Front Pharmacol
Hauptverfasser: Yoshida, Megumi, Yamamiya, Ryodai, Shimizu, Yuto, Yoshimura, Kenjiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550780/
https://ncbi.nlm.nih.gov/pubmed/33117171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.578955
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