STRAP as a New Therapeutic Target for Poor Prognosis of Pancreatic Ductal Adenocarcinoma Patients Mainly Caused by TP53 Mutation

Pancreatic ductal adenocarcinoma (PDAC) has a high mortality rate and poor prognosis. KRAS, TP53, CDKN2A, and SMAD4 are driver genes of PDAC and 30–75% patients have mutations in at least two of these four genes. Herein, we analyzed the relationship between these genes and prognosis of 762 patients...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Oncol
Auteurs principaux: Hu, Shanshan, Chen, Xiao, Xu, Xiangxiang, Zheng, Chenlei, Huang, Wenqian, Zhou, Yi, Akuetteh, Percy David Papa, Yang, Hongbao, Shi, Keqing, Chen, Bicheng, Zhang, Qiyu
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Oncology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550692/
https://ncbi.nlm.nih.gov/pubmed/33134183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.594224
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