Celecoxib Exerts Neuroprotective Effects in β-Amyloid-Treated SH-SY5Y Cells Through the Regulation of Heme Oxygenase-1: Novel Insights for an Old Drug

The formation and aggregation of amyloid-β-peptide (Aβ) into soluble and insoluble species represent the pathological hallmarks of Alzheimer’s disease (AD). Over the last few years, however, soluble Aβ (sAβ) prevailed over fibrillar Aβ (fAβ) as determinant of neurotoxicity. One of the main therapeut...

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Publicat a:Front Cell Dev Biol
Autors principals: Mhillaj, Emanuela, Papi, Massimiliano, Paciello, Fabiola, Silvestrini, Andrea, Rolesi, Rolando, Palmieri, Valentina, Perini, Giordano, Fetoni, Anna Rita, Trabace, Luigia, Mancuso, Cesare
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550645/
https://ncbi.nlm.nih.gov/pubmed/33134292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.561179
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