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Celecoxib Exerts Neuroprotective Effects in β-Amyloid-Treated SH-SY5Y Cells Through the Regulation of Heme Oxygenase-1: Novel Insights for an Old Drug

The formation and aggregation of amyloid-β-peptide (Aβ) into soluble and insoluble species represent the pathological hallmarks of Alzheimer’s disease (AD). Over the last few years, however, soluble Aβ (sAβ) prevailed over fibrillar Aβ (fAβ) as determinant of neurotoxicity. One of the main therapeut...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Mhillaj, Emanuela, Papi, Massimiliano, Paciello, Fabiola, Silvestrini, Andrea, Rolesi, Rolando, Palmieri, Valentina, Perini, Giordano, Fetoni, Anna Rita, Trabace, Luigia, Mancuso, Cesare
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550645/
https://ncbi.nlm.nih.gov/pubmed/33134292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.561179
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