The Polyphenol Pterostilbene Ameliorates the Myopathic Phenotype of Collagen VI Deficient Mice via Autophagy Induction

The induction of autophagy, the catabolic pathway by which damaged or unnecessary cellular components are subjected to lysosome-mediated degradation and recycling, is impaired in Collagen VI (COL6) null mice and COL6-related myopathies. This autophagic impairment causes an accumulation of dysfunctio...

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Bibliographic Details
Published in:Front Cell Dev Biol
Main Authors: Metti, Samuele, Gambarotto, Lisa, Chrisam, Martina, Spina, Martina La, Baraldo, Martina, Braghetta, Paola, Blaauw, Bert, Bonaldo, Paolo
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Cell and Developmental Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550465/
https://ncbi.nlm.nih.gov/pubmed/33134297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.580933
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