The Polyphenol Pterostilbene Ameliorates the Myopathic Phenotype of Collagen VI Deficient Mice via Autophagy Induction

The induction of autophagy, the catabolic pathway by which damaged or unnecessary cellular components are subjected to lysosome-mediated degradation and recycling, is impaired in Collagen VI (COL6) null mice and COL6-related myopathies. This autophagic impairment causes an accumulation of dysfunctio...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Metti, Samuele, Gambarotto, Lisa, Chrisam, Martina, Spina, Martina La, Baraldo, Martina, Braghetta, Paola, Blaauw, Bert, Bonaldo, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550465/
https://ncbi.nlm.nih.gov/pubmed/33134297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.580933
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