Aberrant DNA methylation of PTPRG as one possible mechanism of its under‐expression in CML patients in the State of Qatar

BACKGROUND: Several studies showed that aberrant DNA methylation is involved in leukemia and cancer pathogenesis. Protein tyrosine phosphatase receptor gamma (PTPRG) expression is a natural inhibitory mechanism that is downregulated in chronic myeloid leukemia (CML) disease. The mechanism behind its...

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Detalhes bibliográficos
Publicado no:Mol Genet Genomic Med
Main Authors: Ismail, Mohamed A., Samara, Muthanna, Al Sayab, Ali, Alsharshani, Mohamed, Yassin, Mohamed A., Varadharaj, Govindarajulu, Vezzalini, Marzia, Tomasello, Luisa, Monne, Maria, Morsi, Hisham, Qoronfleh, M. Walid, Zayed, Hatem, Cook, Richard, Sorio, Claudio, Modjtahedi, Helmout, Al‐Dewik, Nader I.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549574/
https://ncbi.nlm.nih.gov/pubmed/32700424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.1319
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