Aberrant DNA methylation of PTPRG as one possible mechanism of its under‐expression in CML patients in the State of Qatar

BACKGROUND: Several studies showed that aberrant DNA methylation is involved in leukemia and cancer pathogenesis. Protein tyrosine phosphatase receptor gamma (PTPRG) expression is a natural inhibitory mechanism that is downregulated in chronic myeloid leukemia (CML) disease. The mechanism behind its...

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Publicat a:Mol Genet Genomic Med
Autors principals: Ismail, Mohamed A., Samara, Muthanna, Al Sayab, Ali, Alsharshani, Mohamed, Yassin, Mohamed A., Varadharaj, Govindarajulu, Vezzalini, Marzia, Tomasello, Luisa, Monne, Maria, Morsi, Hisham, Qoronfleh, M. Walid, Zayed, Hatem, Cook, Richard, Sorio, Claudio, Modjtahedi, Helmout, Al‐Dewik, Nader I.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549574/
https://ncbi.nlm.nih.gov/pubmed/32700424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.1319
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