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Histone deacetylase inhibitors induce medulloblastoma cell death independent of HDACs recruited in REST repression complexes
BACKGROUND: Repressor element 1‐silencing transcription factor (REST) acts as a transcriptional repressor by recruiting several chromatin modifiers, including histone deacetylase (HDAC). Elevated REST expression in medulloblastoma has been associated with tumor progression nevertheless, the tumor sh...
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| Veröffentlicht in: | Mol Genet Genomic Med |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7549561/ https://ncbi.nlm.nih.gov/pubmed/32720471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.1429 |
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