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Survival of a male patient harboring CASK Arg27Ter mutation to adolescence

BACKGROUND: CASK is an X‐linked gene in mammals and its deletion in males is incompatible with life. CASK heterozygous mutations in female patients associate with intellectual disability, microcephaly, pontocerebellar hypoplasia, and optic nerve hypoplasia, whereas CASK hemizygous mutations in males...

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Detalles Bibliográficos
Publicado en:Mol Genet Genomic Med
Main Authors: Mukherjee, Konark, Patel, Paras A., Rajan, Deepa S., LaConte, Leslie E. W., Srivastava, Sarika
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549553/
https://ncbi.nlm.nih.gov/pubmed/32696595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.1426
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