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Non-Cell Autonomous Roles for CASK in Optic Nerve Hypoplasia
PURPOSE: Heterozygous mutations in the essential X-linked gene CASK associate with optic nerve hypoplasia (ONH) and other retinal disorders in girls. CASK(+/−) heterozygous knockout mice with mosaic CASK expression exhibit ONH with a loss of retinal ganglion cells (RGCs) but no changes in retinal mo...
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| Publicado no: | Invest Ophthalmol Vis Sci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Association for Research in Vision and Ophthalmology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6701874/ https://ncbi.nlm.nih.gov/pubmed/31425583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.19-27197 |
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