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Report of a germline double heterozygote in MSH2 and PALB2

BACKGROUND: Carriers with pathogenic variants in MSH2 have increased risk to develop colorectal, endometrium, ovarian, and other types of cancer. The PALB2 is associated with breast, ovarian, pancreatic, and prostate cancer. We describe the case of a 42‐year‐old female diagnosed with endometrial can...

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Detalhes bibliográficos
Publicado no:Mol Genet Genomic Med
Main Authors: Agiannitopoulos, Konstantinos, Papadopoulou, Eirini, Tsaousis, Georgios N., Pepe, Georgia, Kampouri, Stavroula, Patsea, Eleni, Lypas, George, Nasioulas, George
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549547/
https://ncbi.nlm.nih.gov/pubmed/32853479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.1242
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