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Expression profiling of DNA methyl transferase I (DNMT1) and efficacy of a DNA-hypomethylating agent (decitabine) in combination with chemotherapy in osteosarcoma

BACKGROUND: Abnormality in the DNA methylation process is one of the hallmarks of cancer. Emerging evidence strongly supports the idea that defects in DNA methyl transferases (DNMTs) are involved in tumor development and progression. This alteration has major effects at the transcription level of va...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Bone Oncol
मुख्य लेखकों: Chaiyawat, Parunya, Sirikaew, Nutnicha, Budprom, Piyaporn, Klangjorhor, Jeerawan, Phanphaisarn, Areerak, Teeyakasem, Pimpisa, Settakorn, Jongkolnee, Pruksakorn, Dumnoensun
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549121/
https://ncbi.nlm.nih.gov/pubmed/33072501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbo.2020.100321
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