Expression profiling of DNA methyl transferase I (DNMT1) and efficacy of a DNA-hypomethylating agent (decitabine) in combination with chemotherapy in osteosarcoma

BACKGROUND: Abnormality in the DNA methylation process is one of the hallmarks of cancer. Emerging evidence strongly supports the idea that defects in DNA methyl transferases (DNMTs) are involved in tumor development and progression. This alteration has major effects at the transcription level of va...

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Dettagli Bibliografici
Pubblicato in:J Bone Oncol
Autori principali: Chaiyawat, Parunya, Sirikaew, Nutnicha, Budprom, Piyaporn, Klangjorhor, Jeerawan, Phanphaisarn, Areerak, Teeyakasem, Pimpisa, Settakorn, Jongkolnee, Pruksakorn, Dumnoensun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549121/
https://ncbi.nlm.nih.gov/pubmed/33072501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbo.2020.100321
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