Expression profiling of DNA methyl transferase I (DNMT1) and efficacy of a DNA-hypomethylating agent (decitabine) in combination with chemotherapy in osteosarcoma

BACKGROUND: Abnormality in the DNA methylation process is one of the hallmarks of cancer. Emerging evidence strongly supports the idea that defects in DNA methyl transferases (DNMTs) are involved in tumor development and progression. This alteration has major effects at the transcription level of va...

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Detalhes bibliográficos
Publicado no:J Bone Oncol
Main Authors: Chaiyawat, Parunya, Sirikaew, Nutnicha, Budprom, Piyaporn, Klangjorhor, Jeerawan, Phanphaisarn, Areerak, Teeyakasem, Pimpisa, Settakorn, Jongkolnee, Pruksakorn, Dumnoensun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549121/
https://ncbi.nlm.nih.gov/pubmed/33072501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbo.2020.100321
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