Expression profiling of DNA methyl transferase I (DNMT1) and efficacy of a DNA-hypomethylating agent (decitabine) in combination with chemotherapy in osteosarcoma

BACKGROUND: Abnormality in the DNA methylation process is one of the hallmarks of cancer. Emerging evidence strongly supports the idea that defects in DNA methyl transferases (DNMTs) are involved in tumor development and progression. This alteration has major effects at the transcription level of va...

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Bibliografiska uppgifter
I publikationen:J Bone Oncol
Huvudupphovsmän: Chaiyawat, Parunya, Sirikaew, Nutnicha, Budprom, Piyaporn, Klangjorhor, Jeerawan, Phanphaisarn, Areerak, Teeyakasem, Pimpisa, Settakorn, Jongkolnee, Pruksakorn, Dumnoensun
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2020
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549121/
https://ncbi.nlm.nih.gov/pubmed/33072501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbo.2020.100321
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