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Impact of Allosteric Modulation in Drug Discovery: Innovation in Emerging Chemical Modalities

[Image: see text] Recent years have seen an unprecedented level of innovation in allosteric drug discovery and development, with multiple drug candidates advancing into clinical studies. From early examples of allosteric drugs like GABA(A) receptor modulators (benzodiazepines) in the 1960s to more r...

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Publicado en:ACS Med Chem Lett
Autores principales: Han, Bingsong, Salituro, Francesco G., Blanco, Maria-Jesus
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2020
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549105/
https://ncbi.nlm.nih.gov/pubmed/33062158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00655
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