Generation and validation of recombinant antibodies to study human aminoacyl-tRNA synthetases

Aminoacyl-tRNA synthetases (aaRSs) have long been viewed as mere housekeeping proteins and have therefore often been overlooked in drug discovery. However, recent findings have revealed that many aaRSs have noncanonical functions, and several of the aaRSs have been linked to autoimmune diseases, can...

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Gepubliceerd in:J Biol Chem
Hoofdauteurs: Preger, Charlotta, Wigren, Edvard, Ossipova, Elena, Marks, Carolyn, Lengqvist, Johan, Hofström, Camilla, Andersson, Oskar, Jakobsson, Per-Johan, Gräslund, Susanne, Persson, Helena
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549041/
https://ncbi.nlm.nih.gov/pubmed/32817337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012893
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