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Intersection of the ATF6 and XBP1 ER stress pathways in mouse islet cells

Success or failure of pancreatic beta cell adaptation to ER stress is a determinant of diabetes susceptibility. The ATF6 and IRE1/XBP1 pathways are separate ER stress-response effectors important to beta cell health and function. ATF6α. and XBP1 direct overlapping transcriptional responses in some c...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sharma, Rohit B., Darko, Christine, Alonso, Laura C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549035/
https://ncbi.nlm.nih.gov/pubmed/32788214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014173
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