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Inhibition of SARS–CoV-2 by type I and type III interferons

The recently emerged severe acute respiratory syndrome coronavirus-2 (SARS–CoV-2) is the causative agent of the devastating COVID-19 lung disease pandemic. Here, we tested the inhibitory activities of the antiviral interferons of type I (IFN-α) and type III (IFN-λ) against SARS–CoV-2 and compared th...

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Publicat a:J Biol Chem
Autors principals: Felgenhauer, Ulrike, Schoen, Andreas, Gad, Hans Henrik, Hartmann, Rune, Schaubmar, Andreas R., Failing, Klaus, Drosten, Christian, Weber, Friedemann
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549028/
https://ncbi.nlm.nih.gov/pubmed/32587093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC120.013788
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