Papain-like cysteine proteinase zone (PCP-zone) and PCP structural catalytic core (PCP-SCC) of enzymes with cysteine proteinase fold

There are several families of cysteine proteinases with different folds – for example the (chymo)trypsin fold family and papain-like fold family – but in both families the hydrolase activity of cysteine proteinases requires a cysteine residue as the catalytic nucleophile. In this work, we have analy...

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Veröffentlicht in:Int J Biol Macromol
Hauptverfasser: Denessiouk, Konstantin, Uversky, Vladimir N., Permyakov, Sergei E., Permyakov, Eugene A., Johnson, Mark S., Denesyuk, Alexander I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier B.V. 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7548629/
https://ncbi.nlm.nih.gov/pubmed/33058970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijbiomac.2020.10.022
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