Astrocyte- and Neuron-Derived CXCL1 Drives Neutrophil Transmigration and Blood-Brain Barrier Permeability in Viral Encephalitis

Herpes simplex virus (HSV)-1 encephalitis has significant morbidity partly because of an over-exuberant immune response characterized by leukocyte infiltration into the brain and increased blood-brain barrier (BBB) permeability. Determining the role of specific leukocyte subsets and the factors that...

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Udgivet i:Cell Rep
Main Authors: Michael, Benedict D., Bricio-Moreno, Laura, Sorensen, Elizabeth W., Miyabe, Yoshishige, Lian, Jeffrey, Solomon, Tom, Kurt-Jones, Evelyn A., Luster, Andrew D.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7548103/
https://ncbi.nlm.nih.gov/pubmed/32937134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108150
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