The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood–brain barrier

As researchers across the globe have focused their attention on understanding SARS-CoV-2, the picture that is emerging is that of a virus that has serious effects on the vasculature in multiple organ systems including the cerebral vasculature. Observed effects on the central nervous system include n...

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Bibliographic Details
Published in:Neurobiol Dis
Main Authors: Buzhdygan, Tetyana P., DeOre, Brandon J., Baldwin-Leclair, Abigail, Bullock, Trent A., McGary, Hannah M., Khan, Jana A., Razmpour, Roshanak, Hale, Jonathan F., Galie, Peter A., Potula, Raghava, Andrews, Allison M., Ramirez, Servio H.
Format: Artigo
Language:Inglês
Published: The Author(s). Published by Elsevier Inc. 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547916/
https://ncbi.nlm.nih.gov/pubmed/33053430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.105131
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