The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in vitro models of the human blood–brain barrier

As researchers across the globe have focused their attention on understanding SARS-CoV-2, the picture that is emerging is that of a virus that has serious effects on the vasculature in multiple organ systems including the cerebral vasculature. Observed effects on the central nervous system includes...

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Veröffentlicht in:bioRxiv
Hauptverfasser: Buzhdygan, Tetyana P., DeOre, Brandon J., Baldwin-Leclair, Abigail, McGary, Hannah, Razmpour, Roshanak, Galie, Peter A., Potula, Raghava, Andrews, Allison M., Ramirez, Servio H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310612/
https://ncbi.nlm.nih.gov/pubmed/32587958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.15.150912
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