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Structural insights into assembly of the ribosomal nascent polypeptide exit tunnel

The nascent polypeptide exit tunnel (NPET) is a major functional center of 60S ribosomal subunits. However, little is known about how the NPET is constructed during ribosome assembly. We utilized molecular genetics, biochemistry, and cryo-electron microscopy (cryo-EM) to investigate the functions of...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Wilson, Daniel M., Li, Yu, LaPeruta, Amber, Gamalinda, Michael, Gao, Ning, Woolford, John L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547690/
https://ncbi.nlm.nih.gov/pubmed/33037216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18878-8
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