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The mGluR2/3 agonist pomaglumetad methionil normalizes aberrant dopamine neuron activity via action in the ventral hippocampus

The group 2 metabotropic glutamate receptor (mGluR2/3) agonist, pomaglumetad methionil (POM), showed promise as a novel antipsychotic in preclinical research but failed to show efficacy in clinical trials, though it has been suggested that it may be effective in certain patient populations. Although...

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書目詳細資料
發表在:Neuropsychopharmacology
Main Authors: Sonnenschein, Susan F., Grace, Anthony A.
格式: Artigo
語言:Inglês
出版: Springer International Publishing 2020
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547679/
https://ncbi.nlm.nih.gov/pubmed/32663839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-020-0764-2
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