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Leveraging coronavirus binding to gangliosides for innovative vaccine and therapeutic strategies against COVID-19

Covid-19 is an infectious respiratory disease due to a coronavirus named SARS-CoV-2. A critical step of the infection cycle is the binding of the virus spike S protein to the cellular ACE-2 receptor. This interaction involves a receptor binding domain (RBD) located at the center of the S trimer, whe...

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Détails bibliographiques
Publié dans:Biochem Biophys Res Commun
Auteurs principaux: Fantini, Jacques, Chahinian, Henri, Yahi, Nouara
Format: Artigo
Langue:Inglês
Publié: Elsevier Inc. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547605/
https://ncbi.nlm.nih.gov/pubmed/33097184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2020.10.015
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