Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations

BACKGROUND: Chronic alcohol consumption is associated with neuroinflammation, neuronal damage, and behavioral alterations including addiction. Alcohol-induced neuroinflammation is characterized by increased expression of proinflammatory cytokines (including TNFα, IL-1β, and CCL2) and microglial acti...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Lowe, Patrick P., Morel, Caroline, Ambade, Aditya, Iracheta-Vellve, Arvin, Kwiatkowski, Erica, Satishchandran, Abhishek, Furi, Istvan, Cho, Yeonhee, Gyongyosi, Benedek, Catalano, Donna, Lefebvre, Eric, Fischer, Laurent, Seyedkazemi, Star, Schafer, Dorothy P., Szabo, Gyongyi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547498/
https://ncbi.nlm.nih.gov/pubmed/33036616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01972-5
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