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Stick–slip model for actin-driven cell protrusions, cell polarization, and crawling

Cell crawling requires the generation of intracellular forces by the cytoskeleton and their transmission to an extracellular substrate through specific adhesion molecules. Crawling cells show many features of excitable systems, such as spontaneous symmetry breaking and crawling in the absence of ext...

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Pubblicato in:Proc Natl Acad Sci U S A
Autore principale: Sens, Pierre
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547270/
https://ncbi.nlm.nih.gov/pubmed/32958682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011785117
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