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Projection-specific deficits in synaptic transmission in adult Sapap3-knockout mice
Obsessive-compulsive disorder (OCD) is a circuit disorder involving corticostriatal projections, which play a role in motor control. The Sapap3-knockout (KO) mouse is a mouse model to study OCD and recapitulates OCD-like compulsion through excessive grooming behavior, with skin lesions appearing at...
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| Publié dans: | Neuropsychopharmacology |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer International Publishing
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7547074/ https://ncbi.nlm.nih.gov/pubmed/32585679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-020-0747-3 |
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