Genomic loss in environmental and isogenic morphotype isolates of Burkholderia pseudomallei is associated with intracellular survival and plaque-forming efficiency

BACKGROUND: Burkholderia pseudomallei is an environmental bacterium that causes melioidosis. A facultative intracellular pathogen, B. pseudomallei can induce multinucleated giant cells (MNGCs) leading to plaque formation in vitro. B. pseudomallei can switch colony morphotypes under stress conditions...

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Pubblicato in:PLoS Negl Trop Dis
Autori principali: Saiprom, Natnaree, Sangsri, Tanes, Tandhavanant, Sarunporn, Sengyee, Sineenart, Phunpang, Rungnapa, Preechanukul, Anucha, Surin, Uriwan, Tuanyok, Apichai, Lertmemongkolchai, Ganjana, Chantratita, Wasun, West, T. Eoin, Chantratita, Narisara
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546507/
https://ncbi.nlm.nih.gov/pubmed/32991584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008590
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