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Susceptibility of Clinical Isolates of Burkholderia pseudomallei to a Lipid A Biosynthesis Inhibitor

Burkholderia pseudomallei is the causative agent of melioidosis, a serious infection associated with high mortality and relapse. Current antimicrobial therapy using ceftazidime (CAZ) is often ineffective. Inhibitors of LpxC, the enzyme responsible for lipid A biosynthesis, have potential antimicrobi...

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Detalhes bibliográficos
Publicado no:Am J Trop Med Hyg
Main Authors: Sengyee, Sineenart, Saiprom, Natnaree, Paksanont, Suporn, Limmathurotsakul, Direk, Wuthiekanun, Vanaporn, Chantratita, Narisara
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Tropical Medicine and Hygiene 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508901/
https://ncbi.nlm.nih.gov/pubmed/28719324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.16-0858
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