Comprehensive analysis of clinical Burkholderia pseudomallei isolates demonstrates conservation of unique lipid A structure and TLR4-dependent innate immune activation

Burkholderia pseudomallei is an environmental bacterium that causes melioidosis, a major community-acquired infection in tropical regions. Melioidosis presents with a range of clinical symptoms, is often characterized by a robust inflammatory response, may relapse after treatment, and results in hig...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Negl Trop Dis
Prif Awduron: Sengyee, Sineenart, Yoon, Sung Hwan, Paksanont, Suporn, Yimthin, Thatcha, Wuthiekanun, Vanaporn, Limmathurotsakul, Direk, West, T. Eoin, Ernst, Robert K., Chantratita, Narisara
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2018
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842036/
https://ncbi.nlm.nih.gov/pubmed/29474381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006287
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