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A novel assay for drug screening that utilizes the heat shock response of Caenorhabditis elegans nematodes

Biological organisms respond to environmental stressors by recruiting multiple cellular cascades that act to mitigate damage and ultimately enhance survival. This implies that compounds that interact with any of those pathways might improve organism's survival. Here, we report on an initial att...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chen, Chih-Hsiung, Patel, Rahul, Bortolami, Alessandro, Sesti, Federico
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546469/
https://ncbi.nlm.nih.gov/pubmed/33035268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240255
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