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A novel assay for drug screening that utilizes the heat shock response of Caenorhabditis elegans nematodes

Biological organisms respond to environmental stressors by recruiting multiple cellular cascades that act to mitigate damage and ultimately enhance survival. This implies that compounds that interact with any of those pathways might improve organism's survival. Here, we report on an initial att...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Chen, Chih-Hsiung, Patel, Rahul, Bortolami, Alessandro, Sesti, Federico
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546469/
https://ncbi.nlm.nih.gov/pubmed/33035268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240255
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