Targeting MerTK enhances adaptive immune responses following radiotherapy

INTRODUCTION: The role of MerTK, a member of the Tyro3-Axl-MerTK family of receptor tyrosine kinase, in the immune response to radiotherapy (RT) is unclear. We investigated immune- mediated tumor control following RT in murine models of colorectal and pancreatic adenocarcinoma using MerTK wild-type...

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Gepubliceerd in:Int J Radiat Oncol Biol Phys
Hoofdauteurs: Tormoen, Garth W., Blair, Tiffany C., Bambina, Shelly, Kramer, Gwen, Baird, Jason, Rahmani, Ramtin, Holland, John M., McCarty, Owen J.T., Baine, Michael J., Verma, Vivek, Nabavizadeh, Nima, Gough, Michael J., Crittenden, Marka
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546377/
https://ncbi.nlm.nih.gov/pubmed/32311417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2020.04.013
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