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Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in male mice

Neuropsychological deficits, including impairments in learning and memory, occur after spinal cord injury (SCI). In experimental SCI models, we and others have reported that such changes reflect sustained microglia activation in the brain that is associated with progressive neurodegeneration. In the...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Li, Yun, Ritzel, Rodney M., Khan, Niaz, Cao, Tuoxin, He, Junyun, Lei, Zhuofan, Matyas, Jessica J., Sabirzhanov, Boris, Liu, Simon, Li, Hui, Stoica, Bogdan A., Loane, David J., Faden, Alan I., Wu, Junfang
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7545988/
https://ncbi.nlm.nih.gov/pubmed/33052221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.49199
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