Extracellular vesicles derived from Krüppel-Like Factor 2-overexpressing endothelial cells attenuate myocardial ischemia-reperfusion injury by preventing Ly6C(high) monocyte recruitment

Background: The ischemia/reperfusion (I/R) process in patients with ST-segment elevation myocardial infarction (STEMI) triggers an immune response, resulting in myocyte death. Krüppel-Like Factor 2 (KLF2), which is highly expressed in endothelial cells (ECs) under laminar flow, exerts anti-inflammat...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Theranostics
Main Authors: Qiao, Shuaihua, Zhang, Wenfeng, Yin, Yong, Wei, Zhonghai, Chen, Fu, Zhao, Jinxuan, Sun, Xuan, Mu, Dan, Xie, Jun, Xu, Biao
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2020
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7545985/
https://ncbi.nlm.nih.gov/pubmed/33052233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.45459
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