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Native molecule sequencing by nano-ID reveals synthesis and stability of RNA isoforms

Eukaryotic genes often generate a variety of RNA isoforms that can lead to functionally distinct protein variants. The synthesis and stability of RNA isoforms is poorly characterized because current methods to quantify RNA metabolism use short-read sequencing and cannot detect RNA isoforms. Here we...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Maier, Kerstin C., Gressel, Saskia, Cramer, Patrick, Schwalb, Björn
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7545145/
https://ncbi.nlm.nih.gov/pubmed/32887688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.257857.119
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