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HMG-CoA Reductase Inhibitors as Drug Leads against Naegleria fowleri
Primary amebic meningoencephalitis (PAM), caused by the free-living ameba Naegleria fowleri, has a fatality rate of over 97%. Treatment of PAM relies on amphotericin B in combination with other drugs, but few patients have survived with the existing drug treatment regimens. Therefore, development of...
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| Udgivet i: | ACS Chem Neurosci |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7544672/ https://ncbi.nlm.nih.gov/pubmed/32881478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.0c00428 |
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