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Overexpression of Central ACE2 Attenuates the Pressor Response to Chronic Central Infusion of Angiotensin II: A Potential Role for Nrf2

We investigated the mechanism by which ACE2 overexpression alters neurohumoral outflow and central oxidative stress is still unclear. Nuclear factor (erythroid-derived 2)-like2 (Nrf2) is a master antioxidant transcription factor that regulates cytoprotective and antioxidant genes. We hypothesized th...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Ma, Anyun, Gao, Lie, Wafi, Ahmed M., Yu, Li, Rudebush, Tara, Zhou, Wenxian, Zucker, Irving H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7544628/
https://ncbi.nlm.nih.gov/pubmed/32895018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.120.15681
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