Upregulating Nrf2 in the RVLM ameliorates sympatho-excitation in mice with chronic heart failure

Nuclear factor E2-related factor 2 (Nrf2) is a key transcription factor that maintains redox homeostasis by governing a broad array of antioxidant genes in response to oxidant stress. We hypothesized that overexpression of Nrf2 in the rostral ventrolateral medulla (RVLM) ameliorates sympatho-excitat...

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發表在:Free Radic Biol Med
Main Authors: Ma, Anyun, Hong, Juan, Shanks, Julia, Rudebush, Tara, Yu, Li, Hackfort, Bryan T., Wang, Hanjun, Zucker, Irving H., Gao, Lie
格式: Artigo
語言:Inglês
出版: 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718296/
https://ncbi.nlm.nih.gov/pubmed/31181253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2019.06.002
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